Halt
Hangxiety

After Party is composed of a whopping 1000mg of dihydromyricetin.

Dihydromyricetin (DHM) is a natural plant extract which is often taken for its ability to support liver health. 

What Exactly is a Hangover?

alcohol
ADH
acetaldehyde
ADLDH2*1
acetate
A few things happen when you drink ...

It feels good initially

Alcohol (ethanol - EtOH) increases the neurotransmitter GABA in the brain which makes us feel buzzed and relaxed and calm.

It makes us feel quite bad later

Unfortunately the day after drinking we can feel anxious because we don’t have enough GABA from drinking!

Maybe that anxiety even lasts for a few days. DHM (After Party) increases GABA in a non-addictive way to alleviate hangover anxiety. Our body tries as hard as it can to get rid of alcohol as fast as possible by using enzymes (alcohol dehydrogenase – ADH) to turn it into acetaldehyde (a toxin) and then acetaldehyde dehydrogenase – ALDH) to break that down and remove it through our liver. Acetaldehyde is a toxic substance that causes unpleasant symptoms like nausea, headaches, brain fog, and hot/cold sweats, when it builds up.

After Party (DHM) helps our body break down acetaldehyde.

Why do I get flushed from drinking?

People who experience flushing might have an ALDH enzyme that does not function properly including flushing of the face, hot sensations, nausea and palpitations (an awareness of your heart beating faster than normal).

Scientists have found that DHM (After Party’s high dose ingredient):

  • Triggers the liver to produce more enzymes that break down alcohol like alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH). 
  • Reduces inflammatory agents, called cytokines. (High alcohol consumption leads to the release of cytokines in the liver, which causes cellular damage.)
  • Reduces lipid (fat) accumulation in liver tissue! (High doses of alcohol can negatively impact the liver, leading to an accumulation of fat, increased stress and potentially liver diseases such as cirrhosis.)

What We Provide

Brain Function

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Cognitive

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Overall Wellness

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Mental Clarity

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After Party is composed of the potent extract from:

Hovenia dulcis (Japanese Raisin Tree), a source of dihydromyricetin or DHM (Ampelopsin). An absolutely incredible compound that’s been around in Chinese medicine for thousands of years. It also has added electrolytes.

Users consuming DHM (the main component in After Party) after and/or before alcohol consumption have reported experiencing fewer incidents of headaches, nausea, vomiting, and anxiety than at the same level of alcohol ingestion without consuming DHM. Read about a test on rats here.

Built with Purpose

Resources

Missing Article
This study says: “In total, these findings support the utility of DHM as a dietary supplement to reduce ethanol-induced liver injury via changes in lipid metabolism, enhancement of ethanol metabolism and suppressing inflammation responses to promote liver health,” and “This line of research suggests that DHM acts on multiple pathways to promote liver health and counteract ethanol injury.”
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Resources

Dihydromyricetin As a Novel Anti-Alcohol Intoxication Medication

In this study, the authors found that dihydromyricetin (the main ingredient in After Party) counteracts alcohol intoxication, reduces tolerance to alcohol, helps with hangover anxiety, and reduces the likelihood of seizures. Plus they tested it on drunk rats so it’s a fun read!

Missing Article

This study says: “In total, these findings support the utility of DHM as a dietary supplement to reduce ethanol-induced liver injury via changes in lipid metabolism, enhancement of ethanol metabolism and suppressing inflammation responses to promote liver health,” and “This line of research suggests that DHM acts on multiple pathways to promote liver health and counteract ethanol injury.”

Comparison of Hepatic Detoxification activity and reducing Serum Alcohol

This study shows that DHM (After Party’s main ingredient) seems to reduce blood alcohol levels if taken before drinking! Hovenia dulcis (the plant that After Party is made from) appears to reduce circulating levels of alcohol in the blood when taken before drinking. This works somewhat well when taken during or after alchohol consumption, but is more effective when taken 30 minutes before drinking.

Bioactive constituents of Chinese natural medicines

This study suggests that DHM (After Party’s main ingredient) could be used to fight the stumbling and lack of coordination associated with drinking. The study found that Hovenia dulcis (the plant that After Party is made from) prevents alcohol-induced muscle relaxation in rats.

The Versatile Effects of Dihydromyricetin in Health

This article outlines how DHM (the main ingredient in After Party) is not particularly bioavailable which is why After Party has a high dose of DHM in it! Other supplements have a low dose which is why they’re not as effective.

Missing Article

This study found that people who took Hovenia dulcis (the plant that After Party is made from) experienced less dizziness, headache, nausea, and weakness in their hangovers than people not taking it!

Effect of juice and fermented vinegar from Hovenia dulcis peduncles

This study showed that Hovenia dulcis (the plant that After Party is made from) significantly protects against alcohol-induced liver damage.

Treatment of Chronic Liver Injuries in Mice by Oral Administration of Ethanolic Extract of the Fruit of Hovenia dulcis

This study showed that Hovenia dulcis (the plant that After Party is made from) has the ability to reduce injuries previously made to the liver.

Pharmacological potential of ampelopsin in Rattan tea

Many studies have found that DHM (the key component in After Party) also protects against (first link) (and helps repair - second link) liver damage. DHM has been used for hundreds of years in Chinese medicine to treat liver diseases.

Other Ingredients: Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Silicon Dioxide, Dicalcium Phosphate

WARNING: Do not drink and drive or use this product as an excuse to consume alcohol in an irresponsible manner. Consult your physician before use. Do not use AFTER PARTY if you are pregnant, nursing, or under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use this product and operate heavy machinery until you know how it affects you. Keep out of reach of children. Do not exceed 8 tablets per day.

Supplement Facts

AMOUNT PER SERVING

% DAILY VALUE

Other Ingredients: Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Silicon Dioxide, Dicalcium Phosphate

WARNING: Do not drink and drive or use this product as an excuse to consume alcohol in an irresponsible manner. Consult your physician before use. Do not use AFTER PARTY if you are pregnant, nursing, or under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use this product and operate heavy machinery until you know how it affects you. Keep out of reach of children. Do not exceed 8 tablets per day.

About Smart Drugs™

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